Periodontitis

Periodontal disease is an infectious disease that affects about 70% of the adult population, leading to the destruction of the tooth-supporting tissues due to inflammatory reactions triggered by the bacterial biofilm on dental surfaces. The disease is diagnosed through measuring the depth of periodontal pockets, detecting bleeding, and sometimes identifying the bacterial types present.

Available treatments include non-surgical therapy and combinations with scaling and root planing (SRP) to remove the bacterial biofilm and promote healing.

Although SRP is considered a gold standard treatment for periodontitis and peri-implantitis, exposure of the gingival pockets can allow bacteria to re-colonize the tissues promoting new inflammation that can worsen the clinical picture.

Sterify Gel may find useful application in cases of moderate to advanced chronic periodontal disease as an adjunctive treatment following SRP to improve and accelerate healing parameters and prevent inflammation and recurrent infection. In addition, antimicrobial control action prevents the use of antibiotics and the risk associated with antimicrobial resistance. Such control of periodontal disease also allows the retention of patients who cannot undergo surgical treatment.

Gum disease is linked to diabetes, cardiovascular disease, and other conditions.

Maintaining healthy gums can help prevent other diseases and help you recover from them.

Sterify Gel is a medical device certified under the EU MDR 2017/745 (CE 0426), an effective adjunctive therapy for the treatment of moderate to advanced chronic periodontitis. Its use may provide a viable alternative to antibiotic-based treatments and address the unmet need for more effective periodontal and peri-implant disease management strategies. Further research is needed to confirm these findings and explore the broader implications of the use of medical devices in the management of periodontal disease and antimicrobial resistance.

Results

grafico1

Change in pocket depth in millimeters at 1 month, 2 months and 3 months vs. pre-treatment conditions (n=34). Error bars show standard error of the mean (SEM).* p<0.05

grafico2

Change in clinical attachment level (CAL) in millimeters at 1 month, 2 months and 3 months vs. pre-treatment conditions (n=34). Error bars show SEM.* p<0.05

Sterify Skills

Hamper bacteria colonization

Doesn't create resistance

Promotes tissue regeneration

Stable at room temperature